Q: CJC 1295 w DAC Peptide Structure

CJC-1295 Structure Source: Oxford Academic Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg Molecular Formula: C152H252N44O42 Molecular Weight: 3367.954 g/mol PubChem CID: 56841945 CJC-1295-DAC Structure Source: Oxford Academic Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-DAC Molecular Formula: C152H252N44O42 Molecular Weight: 3647.954 g/mol PubChem CID: 91976842

Q: Product Usage

Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Question 1

CJC 1295 w DAC Peptide Structure

Accepted Answer

CJC-1295 Structure

Source: Oxford Academic

Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.954 g/mol
PubChem CID: 56841945

CJC-1295-DAC Structure

Source: Oxford Academic

Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-DAC
Molecular Formula: C152H252N44O42
Molecular Weight: 3647.954 g/mol
PubChem CID: 91976842

Question 2

What is the Mechanism of Action?

Accepted Answer

CJC-1295 is a synthetic peptide designed to mimic the activity of growth hormone-releasing hormone (GHRH). GHRH stimulates the release of growth hormone (GH) from the pituitary gland, a hormone involved in growth, metabolism, and various physiological processes.

Question 3

What is the Difference Between CJC-1295 and Modified GRF (1-29)?

Accepted Answer

CJC-1295 is a modified version of the first 29 amino acids of GHRH, similar to other GHRH analogs such as Sermorelin. It is particularly similar to modified GRF (1-29), but with some differences in structure. The primary distinction is that CJC-1295, especially when used with DAC (Drug Affinity Complex), has a longer half-life compared to modified GRF (1-29). This allows CJC-1295 to stay in the system longer.

Question 4

What is the Half-Life?

Accepted Answer

CJC-1295 is known for its extended half-life, particularly in its DAC form. The addition of DAC allows CJC-1295 to bind to the protein albumin, which may extend its presence in the body. CJC-1295-DAC has been shown to remain in circulation for a longer period than its non-DAC counterpart and similar peptides like modified GRF (1-29).

1. https://academic.oup.com/jcem/article/91/3/799/2843281

Question 5

What is the Research Status of CJC-1295?

Accepted Answer

CJC-1295 is currently not approved by the FDA for clinical use in humans. It is primarily used for research purposes, and its use in clinical settings remains limited to experimental studies. There are ongoing investigations into its effects, but more robust human trials are required to confirm its safety and efficacy.

https://www.fda.gov/drugs/human-drug-compounding/safety-risks-associated-certain-bulk-drug-substances-nominated-use-compounding
https://www.fda.gov/media/94155/download

Question 6

Safety and Side Effects:

Accepted Answer

While CJC-1295 has been researched for its potential applications, some users have reported side effects, including water retention, injection site reactions, fatigue, or increased hunger. However, more studies are needed to understand the long-term safety profile of the peptide.

Question 7

Product Usage

Accepted Answer

Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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