PCL SLU-PP 332 - 10mL 2mg/mL - Research Use Only
SLU-PP-332 for Sale, Direct from PekCura Labs
When researchers search for SLU-PP-332 for sale, they are usually deciding between a direct manufacturer relationship and a reseller. PekCura Labs sells SLU-PP-332 10mL 2mg/mL (CAS 303760-60-3) directly to laboratories and research facilities across the USA, with 99 percent or higher purity confirmed by independent third-party testing. If you are looking to buy SLU-PP-332 online, or trying to figure out where to buy SLU-PP-332 from a source you can verify, every order ships with a QR-linked Certificate of Analysis tied to the specific batch you receive.
Product Specifications
SLU-PP-332 is supplied as a 10mL, 2mg/mL solution, with a molecular formula of C18H14N2O2 and a molecular weight of 290.3 g/mol. It is manufactured to a research-grade standard of 99 percent purity or higher.
Certificate of Analysis and Third-Party Testing
Every batch of SLU-PP-332 is independently verified by Vanguard Laboratory, an ISO 17025:2017-accredited third-party testing facility, using HPLC and LC-MS assay methods. Each vial links to its batch-specific Certificate of Analysis, including lot number, through an on-vial QR code, so you can confirm identity and purity before you buy.
Purity and Quality Standards
PekCura Labs manufactures SLU-PP-332 to a purity of 99 percent or higher, and purity is not a stated claim alone, it is confirmed independently for every batch through third-party testing rather than relying on internal quality control.
Storage and Handling
SLU-PP-332 is suspended in a PEG3000 solvent and should be stored at room temperature to avoid congealing, with a shelf life of two years from the date of manufacture. As with all PekCura Labs products, handling should be limited to licensed, qualified research professionals.
Shipping and Fulfillment
Once your order is placed, PekCura Labs prioritizes fast shipping to get materials into your lab quickly. Orders are packed in insulated Cool Shield mailers to help protect stability in transit, and orders over $100 qualify for free shipping.
- CAS Number: 303760-60-3
- Molecular Formula: C18H14N2O2
- Molecular Weight: 290.3 g/mol
- ≥99% Purity
- Suspended in PEG3000 solvent. Stored at room temperature to avoid congealing. Shelf life of 2 years.
- Research Grade Laboratory research use only
What is SLU-PP-332?
SLU-PP-332 is a synthetic small molecule agonist selectively targeting estrogen-related receptor alpha (ERRα), a nuclear receptor known to regulate genes involved in mitochondrial biogenesis and oxidative metabolism. Developed through structure-based design from the ERRβ/γ-preferring scaffold GSK4716, SLU-PP-332 exhibits enhanced ERRα activity by exploiting key π-π interactions within the receptor's ligand-binding domain (Billon et al. 2022). The compound demonstrates nanomolar potency (EC₅₀ ~8–98 nM for ERRα) and significantly less activation of ERRβ and ERRγ, establishing its receptor selectivity (Billon et al. 2022; Mahale & Girase 2024).
Functional studies reveal that SLU-PP-332 increases the expression of ERRα target genes such as Pdk4, Ddit4, and Slc25a25, enhancing mitochondrial respiration and biogenesis in C2C12 myocytes (Billon et al. 2022; Nasri 2024). In vivo administration in mice results in elevated oxidative muscle fiber content, increased mitochondrial DNA, and improved markers of oxidative phosphorylation, without observed toxicity. Transcriptomic analysis showed significant overlap between the gene expression signatures induced by SLU-PP-332 and those activated by acute aerobic exercise—most notably in genes regulating energy metabolism and circadian rhythm (Billon et al. 2022). These effects were abrogated in skeletal muscle-specific ERRα knockout models, confirming the compound’s mechanism of action via ERRα (Billon et al. 2022).
References
Billon, C., Sitaula, S., Banerjee, S., Welch, R., Elgendy, B., Hegazy, L., ... & Burris, T. P. (2022). A Synthetic ERRα Agonist Induces an Acute Aerobic Exercise Response and Enhances Exercise Capacity. bioRxiv. https://doi.org/10.1101/2022.10.05.510974
Mahale, B. M., & Girase, A. M. (2024). Unlocking the potential: SLU-PP-332 and the future of exercise enhancement and metabolic health. Research Journal of Science and Technology, 16(4). https://doi.org/10.52711/2349-2988.2024.00047
Nasri, H. (2024). New hopes on “SLU-PP-332” as an effective agent for weight loss with indirect kidney protection efficacy; a nephrology point of view. Journal of Renal Endocrinology, 10, e25143. https://doi.org/10.34172/jre.2024.25143














