Vukojevic, J., Milavić, M., Perović, D., Ilić, S., Čilić, A. Z., Đuran, N., Štrbe, S., Zoričić, Z., Filipčić, I., Brečić, P., Seiverth, S., & Sikirić, P. (2022). Pentadecapeptide BPC 157 and the central nervous system. Neural Regeneration Research/Neural Regeneration Research , 17 (3), 482. https://doi.org/10.4103/1673-5374.320969 Sikiric, P., Gojkovic, S., Krezic, I., Smoday, I. M., Kalogjera, L., Zizek, H., Oroz, K., Vranes, H., Vukovic, V., Labidi, M., Strbe, S., Oreskovic, L. B., Sever, M., Tepes, M., Knezevic, M., Barisic, I., Blagaic, V., Vlainic, J., Dobric, I., . . . Seiwerth, S. (2023). Stable gastric pentadecapeptide BPC 157 may recover Brain–Gut axis and Gut–Brain axis function. Pharmaceuticals , 16 (5), 676. https://doi.org/10.3390/ph16050676 Seiwerth, S., Milavic, M., Vukojevic, J., Gojkovic, S., Krezic, I., Vuletic, L. B., Pavlov, K. H., Petrovic, A., Sikiric, S., Vranes, H., Prtoric, A., Zizek, H., Durasin, T., Dobric, I., Staresinic, M., Strbe, S., Knezevic, M., Sola, M., Kokot, A., . . . Sikiric, P. (2021). Stable gastric pentadecapeptide BPC 157 and wound healing. Frontiers in Pharmacology , 12 . https://doi.org/10.3389/fphar.2021.627533

Information for GHK-CU

GHK-Cu is a naturally occurring tripeptide that forms a stable square-planar complex with divalent copper ions, supporting its role as a redox-inactive copper carrier (Pickart, Vasquez Soltero, and Margolina 2012). It has been shown to regulate gene expression related to extracellular matrix remodeling, oxidative stress response, and proteostasis in in vitro models (Pickart and Margolina 2018; Pickart, Vasquez-Soltero, and Margolina 2015).

References

Pickart, L., and A. Margolina. 2018. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences 19(7):1987.

Pickart, L., J.M. Vasquez-Soltero, and A. Margolina. 2012. The Human Tripeptide GHK Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging. Oxidative Medicine and Cellular Longevity 2012:324832.

Pickart, L., J.M. Vasquez-Soltero, and A. Margolina. 2015. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. BioMed Research International 2015:648108.

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GMP Certificates of Analysis

GHK CU<br>78.66mg<br>Batch V250606-26 016<br>06/20/2025

GHK CU
78.66mg
Batch V250606-26 016
06/20/2025

GHK-CU<br>75.1mg<br>Batch #PKGHK75121024<br>12/10/2024

GHK-CU
75.1mg
Batch #PKGHK75121024
12/10/2024

GHK-CU<br>12mg<br>Batch #PKSS3112924<br>09/11/2024

GHK-CU
12mg
Batch #PKSS3112924
09/11/2024

GHK-CU<br>12.3mg<br>Batch #PKTHYA112924<br>09/11/2024

GHK-CU
12.3mg
Batch #PKTHYA112924
09/11/2024

GHK-CU<br>75.5mg<br>Batch #PKGHK75924<br>09/11/2024

GHK-CU
75.5mg
Batch #PKGHK75924
09/11/2024

Research Certificates of Analysis

GHK-CU<br>79.64mg<br>Task #51740<br>Batch #HGHK-0002<br>11/04/2024

GHK-CU
79.64mg
Task #51740
Batch #HGHK-0002
11/04/2024

GHK-CU Peptide Structure

Source: PubChem

PubChem Identifier: CID 9831891

IUPAC Name: copper;(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoate

Molecular Formula: C28H46CuN12O8

Molecular Weight: 742.3 g/mol

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Product Usage

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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Information for GHK-CU

GMP Certificates of Analysis

Research Certificates of Analysis

GHK-CU Peptide Structure

Product Usage

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