PCL LIPO-C Blend 20mL

$79.99

SKU: LIPO-C Categories: ,

What is LIPO-C Blend?

LIPO-C is an investigational formulation comprising Methionine, Inositol, Choline, L-carnitine, L arginine, and B-complex vitamins. This blend is under evaluation in controlled laboratory settings for its potential relevance in studies involving lipid mobilization, mitochondrial bioenergetics, and hepatocellular integrity.

  • Methionine, a sulfur-containing essential amino acid, is frequently investigated for its function as a methyl group donor and its involvement in the synthesis of S adenosylmethionine, an essential metabolite in transmethylation reactions. It is also implicated in redox balance and the biosynthesis of polyamines (Brosnan and Brosnan 2006).
  • Inositol, particularly myo-inositol, is a key component in phospholipid signaling and membrane dynamics. Investigations into its role in lipid transport and insulin signal transduction have yielded valuable mechanistic insights (Bizzarri et al. 2016; NIH PubChem CID: 892).
  • Choline, a quaternary ammonium compound, is vital for the synthesis of phosphatidylcholine and acetylcholine. Its study in metabolic research primarily relates to its function in lipoprotein export and hepatic lipid regulation (Zeisel and da Costa 2009; NIH PubChem CID: 305).
  • L-carnitine is a quaternary ammonium compound that facilitates the transport of long chain fatty acids into the mitochondria for β-oxidation, thereby supporting cellular energy production. It also assists in removing excess acyl groups from mitochondria, preventing their accumulation. While the body can synthesize L-carnitine from lysine and methionine, certain conditions may render it a conditionally essential nutrient (ODS 2023; PubChem CID: 272).
  • L-arginine, a semi-essential amino acid, is being investigated as a substrate for nitric oxide synthesis, which plays a central role in vascular regulation and immune function. Meta-analyses suggest it may support endothelial activity, modulate immune cell signaling, and contribute to tissue repair through its involvement in collagen and polyamine synthesis (McRae 2016; PubChem CID: 6322).
  • B-complex vitamins, notably B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine), and B12 (cobalamin), play integral roles as coenzymes in numerous catabolic and anabolic reactions. These vitamins are central to studies on mitochondrial function, nucleotide biosynthesis, and neurochemical pathways (Kennedy 2016).

The LIPO-C combination is designed exclusively for preclinical investigational protocols. Its constituent compounds collectively support a multifaceted approach to the study of metabolic flux, mitochondrial dynamics, and biochemical resilience under experimental conditions.

References

Bizzarri, M., Dinicola, S., Bevilacqua, A., & Cucina, A. (2016). Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate. International journal of endocrinology, 2016, 5616807. https://doi.org/10.1155/2016/5616807

Brosnan JT, Brosnan ME. (2006). The sulfur-containing amino acids: an overview. The Journal of Nutrition, 136(6 Suppl), 1636S–1640S.
Kennedy DO. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review. Nutrients, 8(2), 68.

McRae M. P. (2016). Therapeutic Benefits of l-Arginine: An Umbrella Review of Meta-analyses. Journal of chiropractic medicine, 15(3), 184–189. https://doi.org/10.1016/j.jcm.2016.06.002

NIH PubChem Compound Summary for CID: 892, Myo-inositol.
https://pubchem.ncbi.nlm.nih.gov/compound/892

NIH PubChem Compound Summary for CID: 305, Choline.
https://pubchem.ncbi.nlm.nih.gov/compound/305

NIH PubChem Compound Summary for CID: 272, L-Carnitine.
https://pubchem.ncbi.nlm.nih.gov/compound/272

NIH PubChem Compound Summary for CID: 6322, L-Arginine.
https://pubchem.ncbi.nlm.nih.gov/compound/6322

Office of Dietary Supplements - Carnitine. ods.od.nih.gov/factsheets/Carnitine HealthProfessional.

Zeisel SH, da Costa KA. (2009). Choline: an essential nutrient for public health. Nutrition Reviews, 67(11), 615–623.

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