Rahaman, K. A., Muresan, A. R., Min, H., Son, J., Han, H., Kang, M., & Kwon, O. (2024). Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro. Journal of Chromatography. B , 1235 , 124033. https://doi.org/10.1016/j.jchromb.2024.124033 Ho, E. N., Kwok, W., Lau, M., Wong, A. S., Wan, T. S., Lam, K. K., Schiff, P. J., & Stewart, B. D. (2012). Doping control analysis of TB-500, a synthetic version of an active region of thymosin β4, in equine urine and plasma by liquid chromatography–mass spectrometry. Journal of Chromatography a/Journal of Chromatography , 1265 , 57–69. https://doi.org/10.1016/j.chroma.2012.09.043 Maar, K., Hetenyi, R., Maar, S., Faskerti, G., Hanna, D., Lippai, B., Takatsy, A., & Bock-Marquette, I. (2021). Utilizing developmentally essential secreted peptides such as thymosin beta-4 to remind the adult organs of their embryonic State—New directions in Anti-Aging Regenerative Therapies. Cells , 10 (6), 1343. https://doi.org/10.3390/cells10061343

Information for TB-500

TB-500 is a 43 amino acid synthetic analogue of thymosin beta-4 (TB-4), which is found naturally in nearly all mammalian cells. TB-500 is known for its effects on actin protein, cell migration, and wound healing.

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Certificates of Analysis

TB-500<br>11.57mg<br>Task #42402 <br>Batch #05072024<br>05/16/2024

TB-500
11.57mg
Task #42402
Batch #05072024
05/16/2024

TB-500<br>8.19mg<br>Task #42390<br>Batch #04302024<br>05/08/2024

TB-500
8.19mg
Task #42390
Batch #04302024
05/08/2024

TB-500 Peptide Structure

Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Molecular formula: C212H350N56O78S
Molar Mass: 4963.4408
CAS number: 77591-33-4
PubChem: CID 16132341

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What Is TB-500?

Signals metabolic cascade promoting wound healing¹
Increases angiogenesis²
Protects cells against oxidative damage²

Promotes cellular differentiation²
Enhances skeleto-muscular regeneration³

Research Studies

Rahaman, K. A., Muresan, A. R., Min, H., Son, J., Han, H., Kang, M., & Kwon, O. (2024). Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro. Journal of Chromatography. B, 1235, 124033. https://doi.org/10.1016/j.jchromb.2024.124033
Ho, E. N., Kwok, W., Lau, M., Wong, A. S., Wan, T. S., Lam, K. K., Schiff, P. J., & Stewart, B. D. (2012). Doping control analysis of TB-500, a synthetic version of an active region of thymosin β4, in equine urine and plasma by liquid chromatography–mass spectrometry. Journal of Chromatography a/Journal of Chromatography, 1265, 57–69. https://doi.org/10.1016/j.chroma.2012.09.043
Maar, K., Hetenyi, R., Maar, S., Faskerti, G., Hanna, D., Lippai, B., Takatsy, A., & Bock-Marquette, I. (2021). Utilizing developmentally essential secreted peptides such as thymosin beta-4 to remind the adult organs of their embryonic State—New directions in Anti-Aging Regenerative Therapies. Cells, 10(6), 1343. https://doi.org/10.3390/cells10061343

Product Usage

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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