Information for TB-500
TB-500 is a 43 amino acid synthetic analogue of thymosin beta-4 (TB-4), which is found naturally in nearly all mammalian cells. TB-500 is known for its effects on actin protein, cell migration, and wound healing.
Research Certificates of Analysis
11.57mg
Task #42402
Batch #05072024
05/16/2024
8.19mg
Task #42390
Batch #04302024
05/08/2024
GMP Certificates of Analysis
5.9mg
Batch #PKTB5005924
09/10/2024
TB-500 Peptide Structure
Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Molecular formula: C212H350N56O78S
Molar Mass: 4963.4408
CAS number: 77591-33-4
PubChem: CID 16132341
What Is TB-500?
Signals metabolic cascade promoting wound healing1
Increases angiogenesis2
Protects cells against oxidative damage2
Promotes cellular differentiation2
Enhances skeleto-muscular regeneration3
Research Studies
- Rahaman, K. A., Muresan, A. R., Min, H., Son, J., Han, H., Kang, M., & Kwon, O. (2024). Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro. Journal of Chromatography. B, 1235, 124033. https://doi.org/10.1016/j.jchromb.2024.124033
- Ho, E. N., Kwok, W., Lau, M., Wong, A. S., Wan, T. S., Lam, K. K., Schiff, P. J., & Stewart, B. D. (2012). Doping control analysis of TB-500, a synthetic version of an active region of thymosin β4, in equine urine and plasma by liquid chromatography–mass spectrometry. Journal of Chromatography a/Journal of Chromatography, 1265, 57–69. https://doi.org/10.1016/j.chroma.2012.09.043
- Maar, K., Hetenyi, R., Maar, S., Faskerti, G., Hanna, D., Lippai, B., Takatsy, A., & Bock-Marquette, I. (2021). Utilizing developmentally essential secreted peptides such as thymosin beta-4 to remind the adult organs of their embryonic State—New directions in Anti-Aging Regenerative Therapies. Cells, 10(6), 1343. https://doi.org/10.3390/cells10061343
Product Usage
This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
