GMP Retatrutide
Why Choose Us?
Research-Grade
Purity
All peptides have a guaranteed purity of at least 99%.
Manufactured in
the USA
Our top-quality products are manufactured right here in the United States.
Fast
Shipping
Your products arrive at your door quickly. Plus, shipping is free for orders over $100.
Guaranteed
Freshness
Products are stored at -20° and shipped in cool shield bubble mailers.
Independently
Tested
Each batch is independently tested to ensure product purity and dosage.
Why Choose Us?
Research-Grade
Purity
All peptides have a guaranteed purity of at least 99%.
Manufactured in
the USA
Our top-quality products are manufactured right here in the United States.
Fast
Shipping
Your products arrive at your door quickly. Plus, shipping is free for orders over $100.
Guaranteed
Freshness
Products are stored at -20° and shipped in cool shield bubble mailers.
Independently
Tested
Each batch is independently tested to ensure product purity and dosage.
Order Retatrutide
What is Retatrutide?
Retatrutide (LY3437943) is a synthetic peptide engineered as a once-weekly agonist of the GIP, GLP-1, and glucagon receptors. It consists of 39 amino acids conjugated to a C20 fatty diacid moiety, with preferential potency at the GIP receptor and extended half-life enabling weekly administration (Abouelmagd et al., 2025; Jastreboff et al., 2023).
In controlled studies, retatrutide led to significant, dose-dependent reductions in body weight (up to −24.2%), BMI, and waist circumference over 48 weeks, alongside improvements in metabolic markers such as HbA1c, fasting glucose, and blood pressure. These effects are attributed to its multi-receptor mechanism enhancing energy expenditure, insulin secretion, and lipid metabolism (Abouelmagd et al., 2025).
Pharmacologically, retatrutide’s multi-agonist activity is designed to exploit synergistic pathways in metabolic regulation. GIP agonism facilitates lipid handling and insulinotropic effects, GLP-1 activity supports glucose control and satiety signaling, and glucagon receptor activation increases hepatic fat oxidation (Abouelmagd et al., 2025; Jastreboff et al., 2023; Pasqualotto et al., 2024). Together, this receptor triad promotes coordinated modulation of energy balance and glycemic control.
Abouelmagd, A. A., Abdelrehim, A. M., Bashir, M. N., et al. (2025). Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis of randomized controlled trials. Proceedings (Baylor University Medical Center), 38(3), 291–303. https://doi.org/10.1080/08998280.2025.2456441
Pasqualotto, E., Ferreira, R. O. M., Chavez, M. P., et al. (2024). Effects of once-weekly subcutaneous retatrutide on weight and metabolic markers: A systematic review and meta analysis of randomized controlled trials. Metabolism Open, 24, 100321.
https://doi.org/10.1016/j.metop.2024.100321
Jastreboff, A. M., Kaplan, L. M., Frías, J. P., et al. (2023). Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial. The New England Journal of Medicine, 389(6), 514– 526. https://doi.org/10.1056/NEJMoa2301972
FAQs
What Are Peptides?
Peptides are short chains of amino acids linked by peptide bonds. They are considered the building blocks of proteins, differing primarily in size. Proteins typically consist of one or more long polypeptide chains with more than 50 amino acids, whereas peptides usually contain between 2 and 50 amino acids. Their smaller size and specific sequences allow peptides to play various roles in biological systems and research settings.
In nature, peptides have diverse biological functions. They can act as signaling molecules such as hormones or neurotransmitters in many organisms, and they are also present in other biological compounds like antibiotics, which interact with biological systems in complex ways. One commonly cited example is insulin, a naturally occurring peptide with a well-understood structure and function in glucose regulation, studied extensively in biochemical research.
Peptides are widely used in scientific research to study protein interactions, investigate disease mechanisms at the molecular level, and explore cellular communication. Their ability to mimic or inhibit specific protein functions makes them valuable tools in laboratories exploring both fundamental biology and experimental therapeutics.
Researchers also examine peptides for their potential utility in developing advanced diagnostics, delivery systems, and laboratory models. Their specificity, modular structure, and adaptability continue to support innovative research across disciplines, including molecular biology, biochemistry, and pharmacology.
Peptides offered for sale are intended strictly for laboratory research purposes. They are not approved for human consumption, clinical use, or diagnostic purposes.
What is PekCura Labs?
Based in the US, PekCura Labs specializes in providing 99% pure peptides specifically for research purposes. Our dedication to quality, scientific integrity, and transparency is unwavering. Every peptide vial comes with QR codes for instant access to Certificate of Analysis (COAs). These reports provide a thorough breakdown of the batch test results, reinforcing your confidence in the purity and quality of the formulations you receive.
Why Choose PekCura Labs?
Top Quality: Our peptides are manufactured in the US and undergo a rigorous testing process, guaranteeing the highest quality and purity standards in the industry. We exceed industry standards by subjecting each peptide batch to two comprehensive third-party tests.
Transparency: Our unwavering commitment to transparency and quality sets us apart from competition. We prioritize delivering accurate information to our customers, eliminating any uncertainties. We provide a QR code on each vial, granting researchers instant access to batch test results and COAs for complete transparency. Every peptide vial is clearly labeled with the exact milligram amount, providing researchers with confidence in their measurements.
Excellent Customer Service: Our commitment extends beyond transactions; we strive to cultivate long-lasting relationships with our customers. Whether you need assistance, want to provide feedback, or have any inquiries, do not hesitate to contact us at Support@PekCuraLabs.com. We do everything in our power to ensure that our customers are satisfied, even after our products are delivered.
What shipping options does PekCura Labs offer?
To meet your specific needs, we offer a variety of shipping options. Additionally, PekCura Labs offers free shipping on $100+ orders.
We offer three different shipping options:
- UPS Standard Overnight*
- UPS 2Day
- Priority Mail Flat Rate (This is both an option for orders under $100 and the method we use for free shipping on orders over $100.)
* Please note: While we do offer overnight shipping, some cities do not offer UPS overnight on weekends if the order is placed on a Friday. Also, we only ship on business days. If you place your order over the weekend, you will not receive your order the next day. Orders placed on Saturday or Sunday will be shipped overnight on Monday.
What kind of packaging do we use?
We use high quality boxes and insulated mailers to confidently deliver our products to your door. At PekCura Labs, our focus is on ensuring that all peptides reach their destination in perfect condition. If your vial is not in exceptional condition when it arrives send us a message at Support@PekcuraLabs.com for a refund.
What’s the difference between GMP and research-grade peptides?
GMP (Good Manufacturing Practice) is an FDA-mandated certification. It’s the gold standard for the pharmaceutical and compounding industry, ensuring strict regulatory oversight, especially for providers and clinical settings. Yes, GMP peptides are more expensive due to these regulatory requirements, but they’re perfect for those needing to meet compliance in highly regulated environments.
Are research-grade peptides trustworthy?
Of course! Our research-based peptides are still the same high-quality peptides you’ve always known and trusted. They’re domestically sourced, with +99% purity, and they’re ideal for general research purposes. You’ll find the same molecular structure in both GMP and Research-Grade options-the difference lies in the regulatory requirements, not the quality of the product.
We introduced GMP peptides to give our customers more options, especially for those needing them for clinical or regulated use. But if you’re using peptides for research, our Research-Grade Peptides are still an excellent, cost-effective choice.
What is our privacy policy?
Your privacy is of utmost importance to us. Your data is solely utilized for order management and delivering exceptional customer service. We guarantee the confidentiality of your information, preventing any external disclosures. To prevent unauthorized access, we utilize 256 Bit SSL encryption. For a comprehensive understanding, please review our privacy policy.
