Why Choose Us?

3

Research-Grade
Purity

All peptides have a guaranteed purity of at least 99%.

2

Manufactured in
the USA

Our top-quality products are manufactured right here in the United States.

1

Fast
Shipping

Your products arrive at your door quickly. Plus, shipping is free for orders over $100.

4

Guaranteed
Freshness

Products are stored at -20° and shipped in cool shield bubble mailers.

5

Independently
Tested

Each batch is independently tested to ensure product purity and dosage.

Why Choose Us?

3

Research-Grade
Purity

All peptides have a guaranteed purity of at least 99%.

2

Manufactured in
the USA

Our top-quality products are manufactured right here in the United States.

1

Fast
Shipping

Your products arrive at your door quickly. Plus, shipping is free for orders over $100.

4

Guaranteed
Freshness

Products are stored at -20° and shipped in cool shield bubble mailers.

5

Independently
Tested

Each batch is independently tested to ensure product purity and dosage.

GMP Reta Vial Transparent Vial Only

What is Retatrutide?

Retatrutide (LY3437943) is a synthetic peptide engineered as a once-weekly agonist of the GIP, GLP-1, and glucagon receptors. It consists of 39 amino acids conjugated to a C20 fatty diacid moiety, with preferential potency at the GIP receptor and extended half-life enabling weekly administration (Abouelmagd et al., 2025; Jastreboff et al., 2023).

In controlled studies, retatrutide led to significant, dose-dependent reductions in body weight (up to −24.2%), BMI, and waist circumference over 48 weeks, alongside improvements in metabolic markers such as HbA1c, fasting glucose, and blood pressure. These effects are attributed to its multi-receptor mechanism enhancing energy expenditure, insulin secretion, and lipid metabolism (Abouelmagd et al., 2025).

Pharmacologically, retatrutide’s multi-agonist activity is designed to exploit synergistic pathways in metabolic regulation. GIP agonism facilitates lipid handling and insulinotropic effects, GLP-1 activity supports glucose control and satiety signaling, and glucagon receptor activation increases hepatic fat oxidation (Abouelmagd et al., 2025; Jastreboff et al., 2023; Pasqualotto et al., 2024). Together, this receptor triad promotes coordinated modulation of energy balance and glycemic control.

References

FAQs

What Are Peptides?

What is PekCura Labs?

Why Choose PekCura Labs?

What shipping options does PekCura Labs offer?

What kind of packaging do we use?

What’s the difference between GMP and research-grade peptides?

Are research-grade peptides trustworthy?

What is our privacy policy?